Abstract The gravitational S $$ mathcal{S} $$ -matrix defined with an infrared (IR) cutoff factorizes Foosball into hard and soft factors.The soft factor is universal and contains all the IR and collinear divergences.Here we show, in a momentum space basis, that the intricate expression for the soft factor is fully reproduced by two boundary curren

The Notch signaling pathway consists of multiple types of receptors and ligands, whose interactions can be tuned by Fringe glycosyltransferases.A major challenge is to determine how these Jackets/Outerwear components control the specificity and directionality of Notch signaling in developmental contexts.Here, we analyzed same-cell (cis) Notch-ligan

Carmen Almansa,1 Christopher S Frampton,2 José Miguel Vela,1 Steve Whitelock,3 Carlos R Plata-Salamán4 1Esteve Pharmaceuticals, S.A., Parc Cientific Barcelona, Barcelona 08028, Spain; 2Rbar3 Ltd, Cambridge, UK; 3Mundipharma Research Ltd, Cambridge, UK; 4Esteve Pharmaceuticals, S.A., Torre Esteve, Barcelona 08038, S

A sequence of complex conformational changes is required for insulin to bind to the insulin receptor.Recent experimental evidence points to the B chain C-terminal (BC-CT) as the location of these changes in insulin.Here, we present Food Feeder molecular dynamics simulations of insulin that reveal new insights into the structural changes occurring i

The Stationary object of this study is polycrystalline materials containing intercrystalline boundaries in face centered cubic and body centered cubic crystals.A wide variety of geometric characteristics that determine the atomic structure and physical properties of intercrystalline boundaries, gives rise to the expediency of systematization of the